QP & Regulatory Lead - Therapeutic Radio-isotopes

Headline

Lead QP and Regulatory Activities as a new GMP radioisotope facility takes shape 

Highlights

  • Act as Qualified Person (QP) for batch certification and release, ensuring GMP compliance in the production of radioisotopes for targeted radiotherapy 
  • Lead regulatory strategy and dossier preparation, and serve as primary liaison with health authorities and project partners
  • Support the development of our GMP facility and operations across disciplines 

Job description

As part of its growing Targeted Radiotherapy programme, SCK CEN is developing a new GMP facility for radioisotopes production. To support this effort, we are recruiting a QP & Regulatory Lead. 

During the project phase, you will take the lead in establishing the regulatory framework and batch release processes. Your responsibilities include: 

  • Develop the batch release strategy and ensure release processes are GMP-compliant and inspection-ready 
  • Provide regulatory and quality support for manufacturing process development, including risk assessments, criticality analysis, and the definition of a robust control strategy with appropriate documentation
  • Ensure successful acquisition of the manufacturing authorization for the facility
  • Lead regulatory dossier preparation and serve as the main point of contact with external project partners for regulatory affairs
  • Liaise with health authorities during inspections and other regulatory interactions 
  • Support pharmaceutical quality system development and integration
  • Provide regulatory and quality guidance on equipment, procedures, IT systems, validation activities, and review and approve documentation 
  • Organize and oversee training related to your scope of responsibility

Once operations begin, your role will focus on ensuring regulatory compliance, performing batch certification, and supporting continuous improvement: 

  • Perform batch review and make legal release decisions as Qualified Person 
  • Maintain regulatory dossiers and ensure timely updates
  • Act as liaison with health authorities for regulatory notifications, inspections, and formal communication
  • Provide support to ensure day-to-day GMP compliance during manufacturing operations

Job requirements

  • Master’s degree in Industrial Pharmacy or Pharmaceutical Sciences 
  • Official recognition as a Qualified Person under EU regulations, with a minimum of 2 years' hands-on experience in batch certification and GMP-related quality decision-making
  • Accreditation as a radiopharmacist is a plus
  • Experience in regulatory dossier preparation and interaction with health authorities
  • Strong background in GMP compliance, with in-depth knowledge of national and international regulations 
  • Excellent communication, leadership, and documentation skills 
  • A proactive, structured, and hands-on mindset 
  • Ability to work cross-functionally in a multidisciplinary team
  • Willing to work in controlled areas subject to radiation protection measures